Whatever the size, shape, thickness, or color, most people have smooth earlobes.
But have you ever met someone that has a crease in their earlobe—a line that seems to split it in two? That’s known as “Frank’s Sign”.
Not surprisingly, it’s named after the man who first recognized it as something other than a simple skin wrinkle.
Sanford Frank wrote a letter to the New England Journal of Medicine in 1973. In it, he described his research into the correlation between an ear crease and heart disease (1).
Ear Crease And Heart Disease
Many studies have since been performed and the great majority have supported Frank’s research (2). It hasn’t been definitively determined why heart disease may manifest in a fold in the earlobe.
- Lack of blood flow to the ears will cause the lobe to wrinkle. If the blood can’t get through to the ears, there’s a blockage somewhere.
- Elastin and collagen fibers weaken in the ears, indicating a similar weakening of coronary arteries (3).
- The coronary arteries end at the ears; vascular disease there means vascular disease further up the line (4, 5).
A Japanese study found that diagonal earlobe crease (DELC) may be caused by shortened cell telomeres associated with metabolic syndrome. It concluded that DELC “might be a useful indirect marker of high-risk patients.” (6).
Telomeres are areas at the end of each strand of DNA that protect cells from damage. The longer the telomere, the better.
A Noticeable Symptom
Interestingly, a noticeable crease in the earlobe is often an indicator of cardiovascular disease in the absence of any other symptoms.
A study published in 2014 tells of a man with hypertension who went to an outpatient clinic. The physician saw Frank’s sign on both earlobes and suggested further testing, although the man displayed no symptoms of heart problems. After testing, it was found that the left main coronary artery was 80% blocked and the right was 90% blocked. “The patient underwent 3-vessel coronary artery bypass graft surgery and has since done well.”
Oddly, prevalence of DELC may be partly cultural/regional.
Another Japanese study found an unarguably strong correlation between ear crease and heart disease. However, the prevalence among the 1000 people involved in the study was less than expected.
“It is concluded that: (1) the prevalence of EC [ear crease] in Japanese adults is very low compared with the results of previous studies in Europe and America; (2) the prevalence of EC tends to increase with advancing age but is unrelated to other risk factors for CHD [coronary heart disease]; (3) a statistically significant association between EC and CHD is seen from multivariate analysis using both clinical and angiographic criteria in the diagnosis of CHD.” (7)
Can Ear Lobes Give Other Signs?
DELC may be a clear tell-tale sign of heart disease, but not when mixed with other conditions. One study aimed to discover if DELC would be a credible identifier of vascular disease and retinopathy in diabetics—it wasn’t (8).
In response, a grading system has been developed for DELC that indicates the severity of current cardiovascular risk:
- Unilateral incomplete – least severe
- Unilateral complete – moderate
- Bilateral complete – most severe (9)
Like a canary in a coal mine, should you notice a permanent crease in someone’s ear, don’t ignore it. Early intervention in the case of heart disease can be a life saver.
- Unhealthy Gut Flora Increases Your Risk of Deadly Diseases such as Stroke and Diabetes
Researchers from Georgia State University have used improved technological approaches to further demonstrate the role that healthy gut flora plays …
- 11 Ways Dehydration Could Be Making You Fat And Sick
The average human body is around 70% water. By not drinking enough water we are causing a whole raft of …
- Fatigue, Vitamin Deficiencies, and Diabetes: 7 Health Problems that Your Hands are Warning You About
The eyes may be the windows to the soul but your hands may be the windows to your blood and …
- Black Lemonade Recipe: The Cleansing Drink That Is So Powerful, You Need To Be Careful When Drinking It
With all the toxins in our environment, it’s a good idea to cleanse your innards every now and then. Sipping …
- Add 2 Tbsp. Of This Coconut Oil Mixture To Your Morning Coffee To Burn A TON Of Calories
Do you drink coffee every morning? If yes, the following coffee creamer recipe is definitely something you’ll want to try (if …
- The 5-Minute Yoga Routine That Can Help Restore Thyroid Levels
Yoga entails more than black stretchy pants and planks. It’s an Eastern practice that goes back thousands of years, an …
- The Real Truth: Antidepressants Actually Deplete These 3 Crucial Nutrients for the Brain
Antidepressants are one of the most prescribed medications out there. But how much do you know about the side effects …
- Sleepless Children Are Aging Faster At A Cellular Level
The importance of sleep is often overlooked but it really can’t be over-emphasized. While you sleep, much of your body …
- Here’s The Homemade Cannabis Oil Recipe That People Are Using as a Chemo Alternative
People have been increasingly becoming aware of the anti-cancer benefits of cannabis over the last few years. Many studies done …
- How To Grow Aloe Vera At Home (And Health Benefits)
Aloe Vera is a member of the Old World succulent group known as Aloaceae. The plant has numerous healing properties …
- 72 Uses For Simple Household Products To Save Money & Avoid Toxins
Many cleaning products available on the market contain harmful toxins. Prolonged use of these products can cause skin irritation and …
- 10 High-Protein Vegetables You Need to Start Eating Today
Protein is the building blocks of muscles as well as bone, skin, hair, and nearly every other part of your …
- 7 Minutes. No Equipment. One Science-Backed Core Workout That Works
Working out is difficult for most people to do on a regular basis. The main issue that arises is making …
- The Many Benefits of Coriander Seed Oil and How to Use It
Coriander is a savory spice used extensively in Asian and Middle Eastern cuisine. It is the seed of the cilantro …
- 4 Diet Mistakes You’re Making that Only Create More Belly Fat
Many people (especially men) find that they accumulate abdominal fat that’s very hard to get rid of. This is especially …