3. Fracture Risk
The FDA has issued warnings about the increased risk of osteoporosis and bone fractures associated to PPI use (10). PPI use of at least 7 years was shown to make patient two times more likely to suffer an osteoporosis-related fracture.
5 years of regular use was associated with an increase risk of hip fractures. Other affected areas included the wrist and spine (11).
4. Nutrient Malabsorption
Stomach acid is important for your body to absorb vitamin B12 and magnesium. Other nutritional deficiencies caused by the drug include calcium and iron (12).
This can lead to:
- Seizures
- Arrhythmias
- Muscle spasms
- Anemia
- Nerve damage
- Psychiatric problems
- Dementia
The FDA has warned that acid reflux medication can cause these problems within the first year of use. Unfortunately, supplements cannot remedy these deficiencies as long as the drugs are still being taken.