1. Vitamin D
That’s why cholesterol-restricting drugs can cause vitamin D deficiency, with symptoms like muscle weakness and pain (8).
Vitamin D also plays a role in preventing weak bones, bone pain, bone loss, hyperparathyroidism. Other benefits of the vitamin include lower blood pressure and cholesterol, diabetes, obesity, muscle weakness, multiple sclerosis, rheumatoid arthritis, chronic obstructive pulmonary disease (COPD), asthma, bronchitis, premenstrual syndrome (PMS), and tooth and gum disease (11).
2. Co-Enzyme Q10
C0q10 is a substance found in every cell in your body. It’s used to produce the energy your body needs to grow and maintain cells.
By the age of 25, your body’s levels of C0Q10 are reduced by half. By the age of 80, your levels are down by another two-thirds (12).
Statins impair C0Q10 production by blocking HMG-CoA reductase, an enzyme required to create the substance (13). Just 2-4 weeks of using the drug reduces your levels of cholesterol and coenzyme Q10 by half (14).
Taking C0Q10 daily for a month can reduce statin-induced muscle pain by 40% (15).
Food sources rich in the nutrient includes organ meats, fish, whole grains, nuts, soybeans, and green vegetables.
3. Vitamin K
The vitamin can reduce the risk of developing coronary heart disease in women aged 49-70 by 9% (18).
Since cholesterol-lowering drugs affect your vitamin K stores, the drugs meant to protect your heart can actually worsen your condition.
Sources of vitamin K1 include cauliflower, broccoli, and green leafy vegetables, while vitamin K2 is found in animal-based foods such as egg yolk, liver and fish liver oils, meats and hard cheeses, as well as fermented foods.
4. Vitamin E
Vitamin E is a fat-soluble antioxidant found in wheat germ oil, avocado, wholegrain cereals, nuts, and seeds.
Regular statin use is known to reduce your body’s vitamin E levels by 17% (19).
Vitamin E alone can significantly reduce the risk of a fatal heart attack by up to 16% as well as reduce the risk of coronary heart disease by 24% (20,21). The vitamin even has the ability to fight atherosclerosis, a condition in which plaque builds in the arteries and take a strain on the heart.